AACR Annual Meeting 2019: Recent Progress For Patients With Hard-to-treat and Rare Cancers

Recent advances in cancer research has led to enormous progress against many cancer types. From 1991 to 2015, we witnessed a 26 percent reduction in the U.S. cancer death rate, representing over 2 million lives saved. Deaths from several common cancers, including breast, lung, prostate, and colorectal cancers, have declined in recent years, which is attributed to smoking cessation, advances in early detection, and treatment improvements.

Progress against many other cancers, however, has been much slower. Death rates for some types of cancer, such as esophageal cancer, have increased in certain populations, and pancreatic cancer is projected to become the second leading cause of cancer-related mortality by 2030.  

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Joint Workshop Leads to Recommendations on Novel Drug-Radiation Combinations

Radiotherapy is a mainstay of cancer treatment. In recent years, improved technology has allowed many cancer patients to receive more targeted doses of radiation, which can improve efficacy and spare …

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FDA Approves Targeted Therapy Combo for Thyroid Cancer

On May 4, the U.S. Food and Drug Administration (FDA) approved a combination of molecularly targeted therapeutics for the treatment of a certain type of thyroid cancer. Specifically, the FDA approved the use of dabrafenib (Tafinlar) in combination with trametinib (Mekinist) for treating patients who have anaplastic thyroid cancer that cannot be removed by surgery or that has metastasized, and that tests positive for a BRAF V600E gene mutation.

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AACR Annual Meeting 2018: Novel Immunotherapy Combinations to Combat Resistance to Checkpoint Inhibition

An exciting area in drug development, immunotherapy is being increasingly utilized by patients with different cancer types. These treatments work by stimulating the patient’s immune system to effectively target and …

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