SABCS to Showcase Advances in Breast Cancer Treatments

Editor’s note: When the San Antonio Breast Cancer Symposium (SABCS) kicks off next week, researchers will present the results of dozens of clinical trials. Among several eagerly anticipated studies is a phase II trial of the TKI inhibitor tucatinib, given in combination with trastuzumab (Herceptin) and capecitabine.

A version of this article on the tucatinib trial is freely available on the Cancer Discovery website, where you can find further coverage of SABCS throughout the meeting.

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Targets Conference Showcases Exciting Data from Clinical Trials of Innovative Cancer Therapeutics

There has been an explosion in the number of cancer therapeutics and clinical trials in the recent past, owing to our ability to better define the molecular targets of different cancers using cutting-edge technologies. Unlike in the past, data from early-stage clinical trials are getting more attention lately because the efficacy of a therapeutic, traditionally evaluated in later-phase trials, is often becoming evident earlier in the course of clinical testing.

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AACR Journals Editors’ Picks for October

As October comes to a close, it’s time for our latest edition of Editors’ Picks. This monthly staple is a collection of 10 “must read” articles that have been hand-selected by the editors from the portfolio of journals published by the AACR. This month, featured articles include results from three clinical trials and a look at cancer disparities among American Indians and Alaska Natives, among others. As always, articles highlighted here are freely available for a limited time.

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ESPN Reporter Holly Rowe Works Through Cancer

Sports are often referred to as a metaphor for life. But, for ESPN reporter Holly Rowe, sports are quite literally a way of life. When Rowe was undergoing treatment for desmoplastic melanoma, her passion for sports—and telling athletes’ stories from the sidelines—helped her muscle through her own personal struggles.

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July Editors’ Picks from AACR Journals

As a monthly staple on this blog, we feature the editors’ picks from the 10 journal issues published by the American Association for Cancer Research (AACR). This month, selections include two articles detailing laboratory culture methods to model human cancers, as well as results from two clinical trials, among other studies. Per usual, articles summarized here are freely available for a limited time.

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The Net Widens for Research on Rare Cancer

Rare cancers, when taken all together, make up an estimated 20 to 25 percent of all cancers diagnosed. With more than 1.7 million people in the U.S. expected to be diagnosed with cancer this year, that could mean as many as 400,000 people will learn they have a rare cancer. Often, these patients have few treatment options.

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AACR Annual Meeting 2019: Leaders Share Highlights and Future Direction

One of the world’s largest cancer research conferences, the AACR Annual Meeting 2019, came to an end with a plenary session titled “AACR Annual Meeting 2019 Highlights: Vision for the Future.” Leaders of the AACR provided an overview of the stellar presentations from the meeting on the topics of prevention, early detection, interception, and the latest breakthroughs in cutting-edge basic, translational, and clinical research.

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AACR Annual Meeting 2019: A Record Year for Clinical Trials Presentations

Over the course of AACR Annual Meeting 2019, there were 213 presentations on incredibly exciting clinical trials. This is a record number of clinical trial presentations for an AACR Annual Meeting. The trials presented covered the continuum of cancer treatment, from surgery, to radiotherapy and chemotherapy, to the two newest pillars of cancer care—molecularly targeted therapy and immunotherapy. The final clinical trials plenary session of the Annual Meeting epitomized this diversity by showcasing clinical trials reporting new ways to combine radiotherapy with other types of treatment, and new advances in immunotherapy and molecularly targeted therapy.

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AACR Annual Meeting 2019: Patients as Partners in the Research Process

In the past couple of decades, progress against cancer has created a new generation of survivors. Today, more than 16.9 million people in the United States are cancer survivors. While their experiences are incredibly diverse, many are living well. They work, they tend to their families, they travel … and many are inspired to play a role in the cancer research community.

The Presidential Select Symposium at the AACR Annual Meeting 2019 addressed these crucial roles in a session titled “Engaging Cancer Patients as Partners in the Research Process.” The session was moderated by outgoing AACR President Elizabeth M. Jaffee, MD, Deputy Director of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

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