The Soil for the Seeds: Investigating the Microenvironment of Acute Myeloid Leukemia

As a predoctoral student in the Integrated Biomedical Sciences Graduate Program at The Ohio State University in 2005, Bethany Mundy-Bosse, PhD, had plans to focus her graduate work on basic stem cell biology to enhance and expand her previous research experience in this field. “When I first started working in a research lab, I was working with stem cells,” recalls Mundy-Bosse, “with every intention of continuing on with basic stem cell biology.” However, after attending a course in immunology with renowned physician-scientist Michael Caligiuri, MD, she found herself completely fascinated by this field. It was this course that would ultimately motivate her to shift her career focus toward tumor immunology.

Read More

FDA Approves Two New Treatments for Acute Myeloid Leukemia

This week, the U.S. Food and Drug Administration (FDA) added two new treatments to the armamentarium for hematologic oncologists treating certain groups of patients with acute myeloid leukemia (AML): enasidenib (Idhifa) and Vyxeos. This news is particularly welcome because AML is the form of leukemia with the lowest five-year relative survival rate.

Read More