Examining the Tumor Microenvironment and Metabolism in Ovarian Cancer

Dong-Joo (Ellen) Cheon, PhD, Assistant Professor of Regenerative and Cancer Cell Biology at Albany Medical College and the 2017 AACR Gertrude B. Elion Cancer Research Award grantee, has been working in the field of ovarian cancer her entire career.

She was first introduced to ovarian cancer research as a graduate student at The University of Texas Health Science Center at Houston when she was tasked with generating CA125 knockout mice. CA125, or cancer antigen 125, is a blood serum biomarker routinely used to diagnose and monitor ovarian cancer.

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Can Artificial Intelligence Help Reduce False-positive Mammograms?

In a study published in the AACR’s journal Clinical Cancer Research, a team of scientists from the University of Pittsburgh discuss yet another area of cancer research where artificial intelligence (AI) can potentially solve a decades-long problem: false-positive results and high patient recall rates from breast cancer screening mammography.

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September Editors’ Picks from AACR Journals

As a monthly feature on this blog, we spotlight the 10 articles selected by our editors from each journal issue published by the American Association of Cancer Research (AACR). These journals feature original articles spanning the continuum of cancer research, from basic science discoveries to patient care.

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World Cancer Research Day: New Global Statistics Highlight the Need for Research

Today, September 24, 2018, is World Cancer Research Day. The American Association for Cancer Research (AACR) is proud to join cancer organizations, associations, and researchers from around the world in supporting this global initiative that aims to raise awareness about the importance of cancer research for saving lives.

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AACR Announces the Global Scholar-in-Training Awards

Building upon the success of the African Cancer Researchers Travel Awards, the American Association for Cancer Research is pleased to announce the expansion of this award program and to invite eligible applicants from all low-, lower-middle, and middle-income economy countries (LMIC).

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The Soil for the Seeds: Investigating the Microenvironment of Acute Myeloid Leukemia

As a predoctoral student in the Integrated Biomedical Sciences Graduate Program at The Ohio State University in 2005, Bethany Mundy-Bosse, PhD, had plans to focus her graduate work on basic stem cell biology to enhance and expand her previous research experience in this field. “When I first started working in a research lab, I was working with stem cells,” recalls Mundy-Bosse, “with every intention of continuing on with basic stem cell biology.” However, after attending a course in immunology with renowned physician-scientist Michael Caligiuri, MD, she found herself completely fascinated by this field. It was this course that would ultimately motivate her to shift her career focus toward tumor immunology.

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AACR Project GENIE: More Data, More Participants, and More Progress

AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) recently hit another milestone: the public release of a fourth dataset, which comes on the heels of three prior public data releases, an expansion of the number of participating institutions, and a recent publication, which was among the most read articles in JCO Clinical Cancer Informatics in July, according to the publisher.

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Understanding Immunotherapy Side Effects

Treatment with checkpoint inhibitors is often billed as gentler than chemotherapy—and it is true that immunotherapy doesn’t come with the same acute side effects, such as hair loss, characteristic of many chemotherapy drugs. But checkpoint inhibitors are not without side effects.

In a story published in the summer 2018 issue of Cancer Today, digital editor Kate Yandell discusses what is known about checkpoint inhibitor side effects and how to spot and treat them.

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