Bringing Awareness to Breast Cancer in October

Breast cancer can be a scary diagnosis. Even though mortality rates have declined in recent years in the United States, it is estimated that over 40,000 women and roughly 500 men will die from breast cancer in 2019. Despite progress in developing new treatment modalities for patients with this disease, there is still substantial work to be done in the field.

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Frontiers in Cancer Science: the Singapore Cancer Conference

Providing a forum for innovative cancer researchers around the world, Singapore will hold its 11th Frontiers in Cancer Science (FCS) conference from November 4-6 at Academia at SingHealth.

The conference is jointly organized by the Cancer Science Institute of Singapore, Duke-NUS Medical School, Genome Institute of Singapore, Institute of Molecular and Cell Biology, Lee Kong Chian School of Medicine, National Cancer Centre Singapore, and National University Cancer Institute, Singapore.

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AACR Meeting Highlights Recent Advances in Pediatric Cancer Research

Pediatric cancer, while rare, is a devastating diagnosis that is estimated to affect over 11,000 children in the United States in 2019. Among those diagnosed between birth and age 14, more than 1,000 are anticipated to die from the disease this year. The most common types of cancer in this age group are leukemias, brain and other central nervous system (CNS) tumors, and lymphomas.

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From the Journals: Editors’ Picks for September

As we welcome the fall season, it’s time for our September edition of Editors’ Picks, a monthly collection of articles hand-picked by the editors of the eight scientific journals published by the AACR. This month, articles span from an assessment of a first-in-class antibody-drug conjugate targeting the antigen CD205 in xenograft models, to results from a clinical trial evaluating the dual inhibition of VEGFR2 and MET in patients with advanced solid tumors. Read on to learn about this month’s selections, which are freely available for a limited time.

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“It Doesn’t Have to be This Way”: Targeting Cancer Health Disparities

The 12th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved kicked off Friday evening in San Francisco with a passionate call to fight cancer disparities on every front, from socioeconomic to biological.

“Everyone in this room is united in our goal to eliminate cancer health disparities,” said conference cochair Phyllis Pettit Nassi, MSW, manager of Special Populations and Native American Outreach at Huntsman Cancer Institute in Salt Lake City. “Medical research powers our ability to treat our patients. Conferences such as this, where we unite as a community, fuel hope that we can improve the lives of our patients.”

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Orchestrating an Antitumor Immune Response: A Preview of the Fifth International Cancer Immunotherapy Conference

Immunotherapy is a form of cancer treatment that helps a patient’s own immune system recognize and attack cancer cells. Research on different types of immunotherapy has exploded over the past decade, and such approaches have proven to be successful for many patients. However, challenges remain, including a lack of response in some patients, development of resistance, and difficulties using certain immunotherapies in solid tumors.

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AACR Cancer Progress Report 2019: Harnessing Research Discoveries for Patient Benefit

Today, the American Association for Cancer Research (AACR) released its ninth annual Cancer Progress Report. The report highlights how research largely supported by federal investments in the National Institutes of Health (NIH) is spurring improvements in public health and innovative breakthroughs across the spectrum of cancer care.

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The Right Dose: Researching Cancer Treatment De-Escalation

Cancer researchers often focus on developing novel treatments or combining therapies in new ways, all with the goal of lengthening survival for patients. But some cancer research has a different goal: to reduce the amount and intensity of treatment patients receive while maintaining equally good cancer outcomes. In the summer 2019 issue of Cancer Today, digital editor Kate Yandell writes about the challenges and successes of this approach, called treatment de-escalation.

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Recent Studies Tap Into AACR Project GENIE Registry

The AACR Project Genomics Evidence Neoplasia Information Exchange (AACR Project GENIE) is a unique registry that aggregates, harmonizes, and links clinical-grade cancer genomic data with clinical outcomes from tens of thousands of cancer patients. AACR Project GENIE recently released its sixth data set, increasing the database to nearly 70,000 de-identified genomic records. The database now has information spanning more than 80 major cancer types, including data from more than 11,000 patients with lung cancer, over 9,700 patients with breast cancer, and nearly 7,000 patients with colorectal cancer.

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