New AACR-Novocure Funding Initiatives Support Tumor Treating Fields Research

Earlier this year, the American Association of Cancer Research (AACR) partnered with Novocure, a global oncology company, to launch several new funding initiatives to support innovative research focused on Tumor Treating Fields (TTFields). TTFields is a novel noninvasive cancer therapy approved by the U.S. Food and Drug Administration for the treatment of adults with glioblastoma multiforme (GBM) and malignant pleural mesothelioma (MPM). Patients wear a portable electric field generator that delivers TTFields to tumors via electrodes attached to the skin over the tumor site.

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AACR Journals Editors’ Picks for October

As October comes to a close, it’s time for our latest edition of Editors’ Picks. This monthly staple is a collection of 10 “must read” articles that have been hand-selected by the editors from the portfolio of journals published by the AACR. This month, featured articles include results from three clinical trials and a look at cancer disparities among American Indians and Alaska Natives, among others. As always, articles highlighted here are freely available for a limited time.

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A Look at Liver Cancer

As Greek mythology tells us, the titan Prometheus was punished by the gods for giving fire to man. His sentence? Eternal torture. Each day, an eagle would eat his liver, which would grow back overnight, ready to be devoured by the eagle again the next day.

The liver’s ability to regenerate presumably evolved to protect it from damage from food toxins. However, chronic cycles of liver damage and regeneration can lead to aberrant replication and eventually the development of liver cancer.

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Bringing Awareness to Breast Cancer in October

Breast cancer can be a scary diagnosis. Even though mortality rates have declined in recent years in the United States, it is estimated that over 40,000 women and roughly 500 men will die from breast cancer in 2019. Despite progress in developing new treatment modalities for patients with this disease, there is still substantial work to be done in the field.

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Frontiers in Cancer Science: the Singapore Cancer Conference

Providing a forum for innovative cancer researchers around the world, Singapore will hold its 11th Frontiers in Cancer Science (FCS) conference from November 4-6 at Academia at SingHealth.

The conference is jointly organized by the Cancer Science Institute of Singapore, Duke-NUS Medical School, Genome Institute of Singapore, Institute of Molecular and Cell Biology, Lee Kong Chian School of Medicine, National Cancer Centre Singapore, and National University Cancer Institute, Singapore.

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AACR Meeting Highlights Recent Advances in Pediatric Cancer Research

Pediatric cancer, while rare, is a devastating diagnosis that is estimated to affect over 11,000 children in the United States in 2019. Among those diagnosed between birth and age 14, more than 1,000 are anticipated to die from the disease this year. The most common types of cancer in this age group are leukemias, brain and other central nervous system (CNS) tumors, and lymphomas.

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From the Journals: Editors’ Picks for September

As we welcome the fall season, it’s time for our September edition of Editors’ Picks, a monthly collection of articles hand-picked by the editors of the eight scientific journals published by the AACR. This month, articles span from an assessment of a first-in-class antibody-drug conjugate targeting the antigen CD205 in xenograft models, to results from a clinical trial evaluating the dual inhibition of VEGFR2 and MET in patients with advanced solid tumors. Read on to learn about this month’s selections, which are freely available for a limited time.

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“It Doesn’t Have to be This Way”: Targeting Cancer Health Disparities

The 12th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved kicked off Friday evening in San Francisco with a passionate call to fight cancer disparities on every front, from socioeconomic to biological.

“Everyone in this room is united in our goal to eliminate cancer health disparities,” said conference cochair Phyllis Pettit Nassi, MSW, manager of Special Populations and Native American Outreach at Huntsman Cancer Institute in Salt Lake City. “Medical research powers our ability to treat our patients. Conferences such as this, where we unite as a community, fuel hope that we can improve the lives of our patients.”

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Orchestrating an Antitumor Immune Response: A Preview of the Fifth International Cancer Immunotherapy Conference

Immunotherapy is a form of cancer treatment that helps a patient’s own immune system recognize and attack cancer cells. Research on different types of immunotherapy has exploded over the past decade, and such approaches have proven to be successful for many patients. However, challenges remain, including a lack of response in some patients, development of resistance, and difficulties using certain immunotherapies in solid tumors.

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