Cancer Research Catalyst staff

December Editors’ Picks from AACR Journals

As the year winds down, here’s our final edition of Editors’ Picks for 2019. This regular feature highlights one “must read” article from each journal issue published by the AACR in a given month. This December, articles include results from three clinical trials, an evaluation of a first-in-class FGFR4 inhibitor, and an analysis of breast cancer survival disparities in New Jersey, among others. As always, articles highlighted here are freely available for a limited time.

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2019 in Review: Progress Across Many Areas of Cancer Research

In 2019, research continued to drive progress across the spectrum of cancer care in the form of new and better ways to prevent, detect, diagnose, and treat some of the many diseases we call cancer. Here’s a look at some key developments in drug approvals, immunotherapy, precision medicine, and disparities research.

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Project GENIE Contributes Data on More Than 40,000 New Cancer Cases

The National Cancer Institute’s Genomic Data Commons (GDC) has released data for 44,756 cancer cases from the American Association for Cancer Research’s Project Genomics Evidence Neoplasia Information Exchange, more simply known as AACR Project GENIE. This massive project was launched in 2015 with the goal of building an international, pan-cancer registry with tens of thousands of patients to empower precision oncology.

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SABCS to Showcase Advances in Breast Cancer Treatments

Editor’s note: When the San Antonio Breast Cancer Symposium (SABCS) kicks off next week, researchers will present the results of dozens of clinical trials. Among several eagerly anticipated studies is a phase II trial of the TKI inhibitor tucatinib, given in combination with trastuzumab (Herceptin) and capecitabine.

A version of this article on the tucatinib trial is freely available on the Cancer Discovery website, where you can find further coverage of SABCS throughout the meeting.

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From the Journals: Editors’ Picks for November

Each month, the editors from the portfolio of scientific journals published by the American Association for Cancer Research (AACR) highlight one “must read” article from every journal issue, which we summarize here. This month’s edition is stuffed with studies relating to recent clinical trials, a preclinical investigation of NSAIDs for the inhibition of colon tumor progression, and many more. As always, articles featured here are freely available for a limited time.

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AACR Journals Editors’ Picks for October

As October comes to a close, it’s time for our latest edition of Editors’ Picks. This monthly staple is a collection of 10 “must read” articles that have been hand-selected by the editors from the portfolio of journals published by the AACR. This month, featured articles include results from three clinical trials and a look at cancer disparities among American Indians and Alaska Natives, among others. As always, articles highlighted here are freely available for a limited time.

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AACR Grants Program Funds Diverse Range of Cancer Research

Since its inception in 1993, the American Association of Cancer Research (AACR) Grants Program, in partnership with other nonprofit organizations, foundations, and pharmaceutical companies, has funded groundbreaking basic, translational, and clinical cancer research. In 2019 alone, the AACR awarded more than $12.5 million in grants to support innovative and impactful cancer research projects.

The AACR Grants Program supports researchers at all career levels by awarding fellowships, career development awards, independent investigator awards, team science awards, and its flagship NextGen Grants for Transformative Cancer Research.

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Learning Lessons From Diverse Populations

The 12th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved wrapped up Monday in San Francisco. This year marked record attendance for the conference, as well as a record number of abstracts that helped shape a dynamic, diverse program.

The meeting reinforced the central dilemma of cancer health disparities: While advances in cancer research have improved outcomes for many Americans, underserved and underrepresented groups have not benefited equally.

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