AACR Team Science Awardees Devise a Method to Detect Common Cancers Early

Early detection of cancer is arguably a holy grail in the field of cancer research. Catching the disease at an early stage could ultimately prevent thousands of deaths from late-diagnosed disease, which is more challenging to treat. Early detection tests exist for a handful of individual cancers, but no approved method can simultaneously screen for multiple types of cancer.

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FDA Approves Targeted Radiotherapy for Neuroendocrine Tumors

The U.S. Food and Drug Administration (FDA) recently added a new therapeutic to the armamentarium for oncologists treating patients with neuroendocrine tumors. The new therapeutic—lutetium (Lu) 177 dotatate (Lutathera)—is a targeted form of systemic radiotherapy.

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Women in Science: AACR Leaders Share Their Stories

In honor of International Day of Women and Girls in Science, a United Nations initiative aimed at narrowing a global gender gap in the scientific work force, several AACR leaders shared how they initially became interested in science, how they built rewarding careers in cancer research, and how they might advise a girl or young woman considering a career in science.

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World Cancer Day: Get the Facts

The American Association for Cancer Research (AACR) is proud to support World Cancer Day, a yearly initiative of the Union for International Cancer Control (UICC). Each February 4, World Cancer Day serves as a rallying cry to raise awareness of the global battle against cancer and of the need for government leaders to make cancer research, prevention, and treatment a national priority.

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Disrupting a Link Between Obesity and Cancer

The obesity epidemic shows no signs of abating. The World Health Organization estimates that the proportion of the world’s population who are obese nearly tripled between 1975 and 2016, with the proportion of adults age 18 or older who are obese reaching 13 percent in 2016. The prevalence of obesity is even higher in the United States.

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Team Science: A Winning Approach to Research

In 1993, Jon R. Katzenbach and Douglas K. Smith authored The Wisdom of Teams, a collection of observations and insights into how high-performance teams can be assembled and managed. Many of the principles elaborated in the book are applicable to team science for cancer research.

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How is Obesity Linked to Cancer?

Medical risks of obesity include high blood pressure, type 2 diabetes, and cardiovascular diseases. Additionally, obesity has been associated with increased cancer incidence and mortality. To address the link between obesity and cancer, the American Association of Cancer Research is hosting a Special Conference, Obesity and Cancer: Mechanisms Underlying Etiology and Outcomes, this week in Austin, Texas.

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Can Molecular Analysis be Tapped to Tackle Brain Cancer?

Compared to treatment advances for other types of cancer, progress in treating brain cancer has been frustratingly slow. Still, understanding the molecular changes that drive brain cancer remains “potentially transformative,” says Paul Mischel, a cancer biologist and neuropathologist at the Ludwig Institute for Cancer Research in San Diego.

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FDA Approves First Targeted Therapeutic for BRCA-mutant Breast Cancer

On Friday, the U.S. Food and Drug Administration (FDA) approved the molecularly targeted therapeutic olaparib (Lynparza) for treating certain patients with metastatic, HER2-negative breast cancer. The FDA also granted marketing authorization for a test to identify those patients eligible to receive olaparib: patients with an inherited, cancer-associated BRCA1 or BRCA2 (BRCA1/2) mutation.

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