Karen Honey, PhD

As senior managing editor, science communications, Karen Honey, PhD, helps the AACR communicate scientific information to the public and educate the public about the importance of lifesaving cancer research. Before joining the AACR, Honey spent eight years working as an editor for two peer-reviewed scientific journals, first Nature Reviews Immunology and then The Journal of Clinical Investigation. During this time, she focused on communicating scientific discoveries to readers with all levels of knowledge, from the lay reader to the scientific expert. Before entering the world of science communication, Honey was a postdoctoral fellow in the laboratory of world-renowned immunologist Alexander Rudensky. She was born in the United Kingdom and received her doctorate in transplantation immunology from the University of Oxford. Honey currently lives in the Philadelphia suburbs.

FDA Approves Targeted Therapy Combo for Thyroid Cancer

On May 4, the U.S. Food and Drug Administration (FDA) approved a combination of molecularly targeted therapeutics for the treatment of a certain type of thyroid cancer. Specifically, the FDA approved the use of dabrafenib (Tafinlar) in combination with trametinib (Mekinist) for treating patients who have anaplastic thyroid cancer that cannot be removed by surgery or that has metastasized, and that tests positive for a BRAF V600E gene mutation.

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Why We Need Tailored Tobacco-control Strategies

Cigarette smoking is linked to 18 different types of cancer. It is the leading preventable cause of cancer in the United States, accounting for 19 percent of the 1,570,978 cancers diagnosed in U.S. adults ages 30 and older in 2014, according to the latest research. Another 0.4 percent of the cancer diagnoses in the U.S. that year were attributable to exposure to secondhand smoke.

That’s why February, which is National Cancer Prevention Month, is a good time to raise awareness of the dangers of cigarette smoking and exposure to secondhand smoke.

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FDA Approves Targeted Radiotherapy for Neuroendocrine Tumors

The U.S. Food and Drug Administration (FDA) recently added a new therapeutic to the armamentarium for oncologists treating patients with neuroendocrine tumors. The new therapeutic—lutetium (Lu) 177 dotatate (Lutathera)—is a targeted form of systemic radiotherapy.

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Disrupting a Link Between Obesity and Cancer

The obesity epidemic shows no signs of abating. The World Health Organization estimates that the proportion of the world’s population who are obese nearly tripled between 1975 and 2016, with the proportion of adults age 18 or older who are obese reaching 13 percent in 2016. The prevalence of obesity is even higher in the United States.

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FDA Approves First Targeted Therapeutic for BRCA-mutant Breast Cancer

On Friday, the U.S. Food and Drug Administration (FDA) approved the molecularly targeted therapeutic olaparib (Lynparza) for treating certain patients with metastatic, HER2-negative breast cancer. The FDA also granted marketing authorization for a test to identify those patients eligible to receive olaparib: patients with an inherited, cancer-associated BRCA1 or BRCA2 (BRCA1/2) mutation.

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