Overcoming Drug Resistance: The EGFR Enigma

EGFR square

Currently, anti-EGFR therapies are approved by the U.S. Food and Drug Administration for the treatment of non-small cell lung cancer, squamous cell carcinoma of the head and neck, pancreatic cancer, and colorectal cancer. Most patients receiving anti-EGFR therapies benefit from the treatment, but the challenge they face, as do patients receiving most other targeted therapies, is that their tumors ultimately develop drug resistance. So efforts are underway to develop newer anti-EGFR therapies that can circumvent resistance to existing EGFR inhibitors.

Read More

Powerhouse Collection of Cancer Experts Converge on Capitol Hill to Discuss the Latest in Cancer Research and Precision Medicine

US Capitol Building

Today, the American Association for Cancer Research (AACR), in conjunction with its Fellows of the AACR Academy, Rep. André Carson (D-Ind.), and Rep. David McKinley (R-W.Va.), held a special briefing …

Read More

Eric Rubin, MD, Discusses How the AACR Contributes to Advances for Patients

AACR-FDA workshop on dose-finding of small molecule oncology drugs

AACR membership includes scientists and physicians from across the cancer research enterprise. Whether basic, translational, or clinical researchers, they all share the same goal: to make progress for patients. In this post, Eric Rubin, MD, deputy editor of Clinical Cancer Research, one of the AACR’s eight journals, shares his thoughts on the AACR’s role in developing breakthrough cancer treatments.

Read More

Q&A With Theodore Lawrence, MD, PhD, on the Launch of the AACR Radiation Science and Medicine Working Group

Theodore Lawrence MD PhD_sq

Over 50 percent of all cancer patients will receive radiation therapy during the course of their treatments. This fact highlights the enormous need to understand how cancer cells respond to radiation and how this biological knowledge may be translated into improved treatments and prolonged patient survival. To support this vital area, the AACR has formed a new scientific working group, the AACR Radiation Science and Medicine (RSM) Working Group.

Read More